# ICSI

> Citation bundle for ICSI on The Treatment Registry.
> URL: https://thetreatmentregistry.com/procedures/icsi
> Bundle URL: https://thetreatmentregistry.com/api/citations/procedures/icsi

- Category: ivf-fertility

## Description

Intracytoplasmic sperm injection is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus.

## Overview

Intracytoplasmic sperm injection is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus. With this method, the acrosome reaction is skipped.

*Reference text adapted from Wikipedia under CC BY-SA 4.0. Verify with a qualified clinician before treatment.*

## FAQs

### Why IVF (in vitro fertilisation) is done?

IVF (in vitro fertilisation) is a type of [fertility treatment](https://www.nhs.uk/conditions/infertility/).

### How well it works?

Your chance of having a baby using IVF can depend on many factors such as:

### What happens during IVF (in vitro fertilisation)?

A full cycle of IVF (in vitro fertilisation) takes around 3 to 6 weeks to complete. It usually follows 6 steps, depending on the type of treatment you’re having.

## Alternative treatments

- **Conventional IVF** — Appropriate when sperm parameters are adequate; lower fertilisation manipulation.
- **Donor sperm IVF** — When severe male-factor cannot be overcome by ICSI; ethical/relational considerations.

## Sources

- [ESHRE — Clinical Practice Guidelines (ART, infertility, ICSI, donor cycles)](https://www.eshre.eu/Guidelines-and-Legal/Guidelines) — European Society of Human Reproduction and Embryology (accessed 2026-06-29)