# PGT-M

> Citation bundle for PGT-M on The Treatment Registry.
> URL: https://thetreatmentregistry.com/procedures/pgt-m
> Bundle URL: https://thetreatmentregistry.com/api/citations/procedures/pgt-m

- Category: ivf-fertility

## Description

Preimplantation genetic diagnosis is the genetic profiling of embryos prior to implantation, and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis.

## Overview

Preimplantation genetic diagnosis is the genetic profiling of embryos prior to implantation, and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development.

*Reference text adapted from Wikipedia under CC BY-SA 4.0. Verify with a qualified clinician before treatment.*