# SADI-S

> Citation bundle for SADI-S on The Treatment Registry.
> URL: https://thetreatmentregistry.com/procedures/sadi-s
> Bundle URL: https://thetreatmentregistry.com/api/citations/procedures/sadi-s

- Category: weight-loss

## Description

Bariatric surgery is a group of surgical procedures used to manage obesity and related conditions. Long-term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size, reduction of nutrient absorption, or a combination of these.

## Overview

Bariatric surgery is a group of surgical procedures used to manage obesity and related conditions. Long-term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size, reduction of nutrient absorption, or a combination of these. Standard of care procedures include Roux en-Y bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch, from which weight loss is largely achieved by altering gut hormone levels responsible for hunger and satiety, leading to a new hormonal weight set point.

*Reference text adapted from Wikipedia under CC BY-SA 4.0. Verify with a qualified clinician before treatment.*

## FAQs

### What is SADI-S?

SADI-S stands for single-anastomosis duodeno-ileal bypass with sleeve, a bariatric (weight-loss) operation. It combines a sleeve gastrectomy, which reduces the size of the stomach, with a single intestinal bypass that reroutes part of the small intestine. It is intended to support weight loss and improve obesity-related health conditions.

### How does SADI-S work?

It works in two ways: the sleeve reduces the stomach's capacity, and the intestinal bypass reduces the length of intestine that absorbs nutrients, which also affects gut hormones involved in hunger and fullness. It is a modification of the duodenal switch that uses a single intestinal connection rather than two. It is generally regarded as a more complex bariatric procedure.

### Who is a typical candidate?

Bariatric surgery is generally considered for people with obesity that has not responded to non-surgical measures, and eligibility is assessed against established medical criteria. Candidates usually undergo evaluation by a multidisciplinary team before surgery. A surgeon determines whether SADI-S is appropriate for the individual.

### What does recovery generally involve?

SADI-S is performed under general anaesthesia, commonly using keyhole (laparoscopic) techniques, and involves a hospital stay followed by a staged return to normal activity. Patients follow a structured diet that progresses from liquids to solid foods as they heal. Ongoing medical follow-up is an important part of recovery.

### What are the main risks?

As a major operation, recognised risks include bleeding, infection, blood clots, and leakage at surgical connections, along with the general risks of anaesthesia. Because it reduces nutrient absorption, it also carries a longer-term risk of nutritional and vitamin deficiencies. Lifelong nutritional monitoring and supplementation are generally required.

### Are the results permanent, and what does it cost?

SADI-S produces lasting anatomical changes, but long-term results depend on sustained changes to diet and lifestyle and on ongoing medical follow-up. Weight regain is possible if recommended habits are not maintained. Cost varies by clinic and country; see the destinations listed for this procedure.